You’re deep in an intense MMO raid, and every second counts. Having extra commands at your fingertips can mean the difference between victory and defeat. That’s why a gaming mouse with side buttons is a game-changer. In this guide, we’ve reviewed the top models for 2026, focusing on programmable buttons, sensor accuracy, and build quality. Whether you’re into MMOs, MOBAs, or FPS games, we have a pick for you. For more on ergonomics, check out our guide to the best gaming mouse for right handed players.

Buying Guide

Number of Side Buttons

The primary reason to choose a side-button mouse is the number of programmable buttons. MMO players often need 12 side buttons, while FPS gamers might prefer fewer, more accessible buttons. The Redragon M913 offers 12 side buttons, while the Logitech G502 HERO has 11 programmable buttons in total. Consider your gaming style and how many commands you need readily available.

Sensor Performance

A high-quality sensor ensures precise tracking without lag. The Razer Naga V2 HyperSpeed features the Focus Pro 30K optical sensor, while the Logitech G502 HERO uses the HERO 25K sensor. For players with sweaty hands, we recommend reading our best gaming mouse for sweaty hands guide to find a mouse with a grippy surface.

Build Quality and Comfort

Long gaming sessions require a comfortable grip and durable construction. The Redragon M908 includes adjustable weights, and the Logitech G502 also features a weight tuning system. If you have longer fingers, our best gaming mouse for long fingers guide may help you find a shape that fits.

Customization Software

Remapping buttons and adjusting lighting is crucial. Redragon provides its own software for the M913 and M908, while Razer uses Synapse. Logitech G HUB offers extensive customization. Make sure the software is compatible with your system and allows you to save profiles directly to the mouse.

Final Thoughts

After reviewing the top options, we recommend the Redragon M913 Wireless RGB MMO Gaming Mouse 16000 for MMO players who need wireless freedom and 12 side buttons. For FPS gamers seeking a wired option with adjustable weights and a top-tier sensor, the Logitech G502 Hero Wired Gaming Mouse – Black is an excellent choice. Both offer outstanding performance and customization to elevate your gameplay.

Frequently Asked Questions

How many side buttons do I need for MMO gaming? For MMOs, 12 side buttons are ideal to map all your abilities without reaching for the keyboard. Mice like the Redragon M913 or Razer Naga V2 HyperSpeed provide that layout.

Are wireless gaming mice with side buttons reliable? Yes, modern wireless technology such as Razer HyperSpeed offers low latency comparable to wired connections. For more on wireless options, see our best wireless gaming mouse for small hands guide.

Can I use a gaming mouse with side buttons for work? Absolutely. Programmable buttons can be assigned to shortcuts like copy, paste, or application switching, boosting productivity in tasks like video editing or data entry.

What is the best DPI for a gaming mouse with side buttons in 2026? DPI depends on your game and screen resolution. For fast-paced shooters, 16000 DPI or higher gives you quick turns, while lower settings around 800 DPI offer precision for sniping.